Big Ideas: Disorders, Epigenetics, and Gene Silencing

Essential Questions: How do genetic mutations occur? How are scientist using the human genome to understand how genes work?

Vocabulary: gene switches, RNAi, CRISP/Cas, cloning, transgenics, Hela cells, imprinting, epigenetics, H-W principle, genetic frequencies

Month

Content

Skills

Asessment

Standards

Instructional Activities, Strategies, and Differentiation

April

Genetic Expression:

Formative:

Formal Indiana State Core Standards Are Not Available

Provide Topic Reading Assignments and Vocabulary List

* Gene Silencing and Influences (Imprinting, Epigenetics, RNAi, Hardy-Weinberg Principle, Gene Frequencies)

Demonstrate how gene switches are used to turn on genes for various phenotypic characteristics

Deliver Information via Lecture, Discussion and Handouts

Use two analogies to illustrate how RNAi’s used to “interfere” with specific gene expression and protein production.

Student Partipiation and Dialog

However, Some Related State Standards Associated with General Biology Could Apply

Use Technology (ie Simulations/Illustrations/Videos), Various Manipulatives and Word Play

Visit (www.rm118.com) for Further Details and Information with Regards to the Curriculum

Create a presentation based on genetic expression such as gender linkage, non-disjunction of chromosomes,

Study Guide Assignments

Offer Review Opportunities (Study Guides and Study Sessions)

gene mutations, human genome project, gender determinations, epigenetics, and RNAi

Lab Practicles and/or Projects

Visit:https://www.in.gov/doe/students/indiana-academic-standards/science-and-computer-science/

Supplement Topic Discussion with Labs/Projects/Demonstrations

Chapter Quizzes

Reading / Vocabulary Exam

Summative:

Chapter Exam