Big Ideas: Disorders, Epigenetics, and Gene Silencing    
Essential Questions: How do genetic mutations occur? How are scientist using the human genome to understand how genes work?
Vocabulary: gene switches, RNAi, CRISP/Cas, cloning, transgenics, Hela cells, imprinting, epigenetics, H-W principle, genetic frequencies  
Month Content Skills Asessment Standards Instructional Activities,
Strategies, and Differentiation
April Genetic Expression: Formative:  Formal Indiana State Core Standards Are Not Available  Provide Topic Reading Assignments and Vocabulary List   
* Gene Silencing and Influences (Imprinting, Epigenetics, RNAi, Hardy-Weinberg Principle, Gene Frequencies) Demonstrate how gene switches are used to turn on genes for various phenotypic characteristics  Student Partipiation and Dialog  Deliver Information via Lecture, Discussion and Handouts
  Use two analogies to illustrate how RNAi’s used to “interfere” with specific gene expression and protein production. Study Guide Assignments  The Proceeding Are Related State Core Standards Associated with Use Technology (ie Simulations/Illustrations/Videos), Various Manipulatives and Word Play
Visit ( for Further Details and Information with Regards to the Curriculum   Create a presentation based on genetic expression such as gender linkage, non-disjunction of chromosomes,   Lab Practicles and/or Projects General Biology That Can Be Applied To This Discipline/Curriculum: Offer Review Opportunities (Study Guides and Study Sessions)
  gene mutations, human genome project, gender determinations, epigenetics, and RNAi Chapter Quizzes Visit: Supplement Topic Discussion with Labs/Projects/Demonstrations
Reading / Vocabulary Exam
Core Standards:    
Chapter Exam B.1.2, B.5.1, B.5.2, B.5.4, B.5.5, B.5.6, B.7.2, B.7.3, B.7.5
Process Standards:
[x] SEPS.1 Posing Questions
[x] SEPS.2 Developing and Using Models and Tools
[x] SEPS.3 Constructing and Performing Investigations 
[x] SEPS.4 Analyzing and Interpreting Data
[x] SEPS.5 Using Mathematics and Computational Thinking
[x] SEPS.6 Constructing Explanations
[x] SEPS.7 Engaging in Argument from Evidence 
[x] SEPS.8 Obtaining, Evaluating, and Communicating Info
Literacy Standards:
[x] LST.1 Learning Outcomes: 
Read and comprehend science and technical texts  
independently and proficiently and write effectively for a variety 
of discipline-secific tasks, purposes, and audiences
[x] LST.2 Key Ideas and Textual Support
Extract and construct meaning from science and technical texts  
using a variety of comprehension skills
[x] LST.3 Structural Elements and Organization
Build understanding of science and technical texts, using  
knowledge of structural organization and author’s purpose and  
[x] LST.4 Synthesis and Connection of Ideas
Build understanding of science and technical texts by 
synthesizing and connecting ideas and evaluating specific
[x] LST.5 Writing Genres
Write for different purposes and to specific audiences or people
[x] LST.6 The Writing Process
Produce coherent and legible documents by planning, drafting, 
revising, editing, and collaborating with others